Bartertown.com

I recently won a full brick of Galactic Guardians Heroclx boosters, giving 8 regular boosters and the 1 giant-sized booster.

I have real close to no interest in this game and was trying to decide what to do with them.

Will I get more play trading them away unopened or opening them, inventorying them, and then trying to trade the lot?

Any suggestions? I just know that I don't really want them (well, maybe I want a Silver Surfer one).

Ebay.
Unopened.

I agree with kturock. The sure bet is to leave them sealed and ebay them.

If there are ultra-rare chase figures in the set, and you happened to get one...

Of course, every time anyone I know "goes for it", it has always been a letdown. Unopened boxes are so tempting though.

I beleive the set has sold out or is very close to it.
Ask around. Talk to others at the FLGS. You might be able to sell them to players there, unopened.
Check ebay's other ads saying availablity.